Symbol
Name
ID

Tnfrsf13c
tumor necrosis factor receptor superfamily, member 13c
MGI:1919299

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Decreased circulating IgG level	Decreased circulating total IgM	Complete or near-complete absence of specific antibody response to unconjugated pneumococcus vaccine	Abnormal T cell count	Recurrent sinusitis	Recurrent pneumonia	Combined immunodeficiency	Recurrent bacterial infections
Disease(s) Associated with TNFRSF13C
common variable immunodeficiency 4

Mouse Phenotypes

decreased B cell proliferation

decreased T cell proliferation

absent transitional stage B cells

increased immature B cell number

increased pro-B cell number

arrested B cell differentiation

decreased mature B cell number

decreased B-2 B cell number

absent marginal zone B cells

decreased B cell number

increased pre-B cell number

decreased lymphocyte cell number

abnormal lymphocyte physiology

abnormal B cell physiology

decreased IgD level

decreased IgG1 level

decreased IgG2a level

decreased IgG2b level

decreased IgG3 level

decreased IgG level

decreased IgM level

abnormal humoral immune response

decreased interferon-gamma secretion

increased length of allograft survival

Availability

Mouse Genotype

Tnfrsf13c^Bcmd1/Tnfrsf13c^Bcmd1

Tnfrsf13c^m1Btlr/Tnfrsf13c^m1Btlr

Tnfrsf13c^M2Btlr/Tnfrsf13c^M2Btlr

Tnfrsf13c^tm1Mass/Tnfrsf13c^tm1Mass

Tnfrsf13c^tm1Msc/Tnfrsf13c^tm1Msc

Tg(Mx1-cre)1Cgn/0
Tnfrsf13c^tm2.1Mass/Tnfrsf13c^tm2.1Mass (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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